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World Journal of Men's Health · 2014Long-term outcomes

The benefits and risks of testosterone replacement therapy: a review

Traish et al. reviewed long-term observational evidence on testosterone therapy in men with testosterone deficiency, focusing on metabolic health, body composition, sexual function and quality of life.

Traish A. M.Open the publication DOI: 10.1016/j.steroids.2014.05.004

Focus

Long-term outcomes

Published finding

Long-term outcomes

Source

10.1016/j.steroids.2014.05.004

Record

Ref 07

Structured abstract

Method

Traish et al. reviewed long-term observational evidence on testosterone therapy in men with testosterone deficiency, focusing on metabolic health, body composition, sexual function and quality of life.

Result

Long-term therapy was associated with sustained improvements in waist circumference and body composition. Metabolic and sexual-health outcomes improved across the reviewed evidence. The review supports continued monitoring and individual risk assessment.

What to take with you

The reviewed series associate long-term therapy with sustained changes in waist, body composition, metabolic and sexual measures.

Why it matters

Long-term therapy was associated with sustained improvements in waist, body composition, metabolic and sexual measures.

Study frame

Long-term outcomes

Traish et al. reviewed long-term observational evidence on testosterone therapy in men with testosterone deficiency, focusing on metabolic health, body composition, sexual function and quality of life.

Finding

Long-term therapy was associated with sustained improvements in waist circumference and body composition.

Contrast

Metabolic and sexual-health outcomes improved across the reviewed evidence.

Context

The review supports continued monitoring and individual risk assessment.

DOI

10.1016/j.steroids.2014.05.004

Category

Long-term outcomes

Findings listed

3

Type

As published

What to take from the numbers

Boxes below use only wording already in the published summary for this study.

Reported finding

1

Long-term therapy was associated with sustained improvements in waist circumference and body composition.

Reported finding

2

Metabolic and sexual-health outcomes improved across the reviewed evidence.

Reported finding

3

The review supports continued monitoring and individual risk assessment.

A narrative review synthesises existing studies; it does not provide the causal certainty of a large randomised trial.

Why it matters when reading your own result

Pulled from the study's own findings.

Long-term therapy was associated with sustained improvements in waist circumference and body composition.

Long-term outcomes

Metabolic and sexual-health outcomes improved across the reviewed evidence.

Long-term outcomes

The review supports continued monitoring and individual risk assessment.

Long-term outcomes

Clinical reading

How to use this page

Traish et al. reviewed long-term observational evidence on testosterone therapy in men with testosterone deficiency, focusing on metabolic health, body composition, sexual function and quality of life.

Your own numbers

Measure before you decide what this page means for you.

The figures here describe men who were actually measured.

  • Total testosterone and SHBG
  • Symptoms written down
  • Haematocrit as a safety baseline
  • Repeat labs before any protocol change